Sunday 12 July 2015

Congenital Heart Disease 

Congenital heart disease is when you are born with malformations of the heart’s structures. Congenital heart disease is a broad term and examples are holes in the heart, abnormal valves, and abnormal heart chambers.


CLUBBED FINGERNAILS

General signs of congenital heart disease can include:


  • ·    Excessive sweating
  • ·         Extreme tiredness and fatigue      
  • Poor feeding
  • ·         Rapid heartbeat
  • ·         Rapid breathing
  • ·         Shortness of breath
  • ·         Chest pain
  • ·         A blue tinge to the skin (cyanosis)
  • ·         Clubbed fingernails

CYANOSIS
 


















Causes and risk factors 

If your child has a congenital heart defect, you may think you did something wrong during your pregnancy to cause the problem. However, doctors often don’t know why congenital heart defects occur.
Heredity may play a role in some heart defects. For example, a parent who has a congenital heart defect may be more likely than other people to have a child with the defect. Rarely, more than one child in a family is born with a heart defect.Children who has genetic disorders, such as Down syndrome, often have congenital heart defects. In fact, half of all babies who have Down syndrome have congenital heart defects. Besides, smoking during pregnancy also has been linked to several congenital heart defects. Other than that, this may be the result of the genes you inherited from your parents or adverse exposure to certain elements while still in the womb, such as some medicines or too much alcohol.


There are some factors that are associated with an increased chance of having congenital heart disease. These risk factors include:

    ·         Genetic or chromosomal abnormalities in the child, such a Down syndrome
·         Taking certain medications or alcohol or drug abuse during pregnancy
·         Maternal viral infection, such as rubella ( German measles ) in the first trimester or pregnancy
·        
The risk of having a child with congenital heart disease may double if a parent or a sibling has a congenital heart defect.






Tests to diagnose a congenital heart disease 

   ·         Fetal echocardiogram
·         Echocardiogram
·         Electrocardiogram
·         Chest X-ray
·         Pulse oximetry
·        
Cardiac catheterization



Treatment - Pharmacology 

To treat complications and relive symptoms:

·         Diuretics lower the amount of extra fluid in the body
·         Digoxin increases the strength of the heartbeats
·         Vasodilators widen blood vessels so blood can flow more easily
·         Antiarrhythmics treat and prevent irregular heartbeats

To treat a certain defect

·         Prostaglandins and prostaglandin inhibitorshelp keep open or close a fetal blood vessel, called the ductus arteriosus, that normally closes at birth

To prevent problems

·         Antibiotics before certain dental and surgical procedures help prevent endocarditis in some people
·         Blood thinners, such as aspirin or anticoagulants - lower the risk of blood clots in the heart or in blood vessels



Extra Information – Statistic 


The Baltimore-Washington Infant Study is a regional epidemiologic study of congenital heart disease. Among infants born in the study area in 1981 and 1982, 664 had a diagnosis of congenital heart disease confirmed in the first year of life by echocardiography, cardiac catheterization, cardiac surgery, or autopsy. The prevalence rate was 3.7/1,000 livebirths for all cases and 2.4/1,000 livebirths for cases confirmed by invasive methods only. Diagnosis-specific prevalence rates of congenital heart disease are compared with those of eight previous case series. Changing diagnostic categorizations in the time span covered and methodological differences resulted in great variation of the data. However, the data of the New England infant Cardiac Program which used the same case discovery methods showed similar occurrences of major morphologic abnormalities, suggesting that these are stable basic estimates in the eastern United States. For all case series, the rate of confirmed congenital heart disease was approximately 4/1,000 livebirths over the 40-year time span.




REFERENCE






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